Data Sheet 产品使用指南
Recombinant Human Interleukin-5 Receptor alpha (CHO-expressed)是白细胞介素-5受体的亚基。
Synonyms
rHuIL-5Rα; IL-5R; IL-5RA; CD125 ; 重组人白细胞介素-5受体α (CHO表达)
Species
HumanSource
CHO Accession
Q01344 Gene ID
3568 Molecular Weight
53-56 kDa AA Sequence
DLLPDEKISL LPPVNFTIKV TGLAQVLLQW KPNPDQEQRN VNLEYQVKIN APKEDDYETR ITESKCVTIL HKGFSASVRT ILQNDHSLLA SSWASAELHA PPGSPGTSIV NLTCTTNTTE DNYSRLRSYQ VSLHCTWLVG TDAPEDTQYF LYYRYGSWTE ECQEYSKDTL GRNIACWFPR TFILSKGRDW LAVLVNGSSK HSAIRPFDQL FALHAIDQIN PPLNVTAEIE GT Biological Activity
The ED50 is <0.2 ng/mL as measured by TF-1 cells. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Interleukin-5 Receptor alpha (CHO-expressed) (rHuIL-5Rα) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Human Interleukin-5 Receptor alpha (CHO-expressed) (rHuIL-5Rα) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Interleukin-5 Receptor (IL5R) consists of an α chain corresponding to the low affinity IL5 binding site (Kd= 1 nM), and a β chain (130 kd component) that associates with the α chain to form the high affinity binding site (Kd= 0.05 nM)[1]. |
