Recombinant Mouse KGF/FGF-7是属于成纤维细胞生长因子家族的多肽有丝分裂原，仅与FGFR2的剪接变体 (FGFR2 IIIb) 结合，并且是上皮细胞的高度特异性旁分泌生长因子。 KGF/FGF-7及其受体对正常伤口愈合很重要。
Synonyms
rMuKGF/FGF-7; Fibroblast Growth Factor-7; HBGF-7
Species
MouseSource
E. coli Accession
P36363 Gene ID
14178 Molecular Weight
Approximately 18.7 kDa AA Sequence
CNDMSPEQTA TSVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNSYNIMEIR TVAVGIVAIK GVESEYYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHSGG EMFVALNQKG IPVKGKKTKK EQKTAHFLPM AIT Biological Activity
The ED50 is <2 ng/mL as measured by 4MBr-5 cells, corresponding to a specific activity of >5.0 × 105 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse KGF/FGF-7 (rMuKGF/FGF-7) to 100 μg/mL using PBS. Storage & Stability
Lyophilized recombinant Mouse KGF/FGF-7 (rMuKGF/FGF-7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Recombinant Mouse KGF/FGF-7 is a polypeptide mitogen that belongs to the family of fibroblast growth factors. It binds only to a splice variant of FGFR2 (FGFR2 IIIb) and is a highly specific paracrine growth factor for epithelial cells. Recombinant Human Keratinocyte Growth Factor 1/FGF-7 and its receptor are important for normal wound healing. |
