Recombinant Human Monocyte Chemotactic Protein-3/CCL7 (CHO-expressed) 是趋化因子和引诱剂，用于各种白细胞，包括单核细胞和嗜中性粒细胞。
Synonyms
rHuMCP-3/CCL7; C-C motif chemokine 7; MCP3; SCYA6; SCYA7 ; 重组人单核细胞趋化蛋白-3/CCL7 (CHO表达)
Species
HumanSource
CHO Accession
P80098 Gene ID
6354 Molecular Weight
10-18 kDa AA Sequence
QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL Biological Activity
The ED50 is <1.5 μg/mL as measured by CHO-K1/Gα15/hCCR1 cells (human Gα15 and human CCR1 stably expressed in CHO-K1 cells). Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Monocyte Chemotactic Protein-3/CCL7 (CHO-expressed) (rHuMCP-3/CCL7) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Human Monocyte Chemotactic Protein-3/CCL7 (CHO-expressed) (rHuMCP-3/CCL7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CCL7 is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses through binding to its receptors to mediate the recruitment of immune cells. Abnormal CCL7 expression is associated with certain immune diseases. CCL7 alsoplays a pivotal role in tumorigenesis[1]. |
