Recombinant Mouse MCP-3/CCL7 (CHO-expressed) 是趋化因子和引诱剂,用于各种白细胞,包括单核细胞和嗜中性粒细胞。 Synonyms rMuMCP-3/CCL7; C-C motif chemokine 7; MCP3; SCYA7 ; 重组小鼠 MCP-3/CCL7 (CHO-表达) Species MouseSource CHO Accession Q03366 Gene ID 20306 Molecular Weight 8-12 kDa AA Sequence QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP Biological Activity The ED50 is <1 μg/mL as measured by CHO-K1/Gα15/mCCR2 cells (human Gα15 and mouse CCR2 stably expressed in CHO-K1 cells). Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse MCP-3/CCL7 (CHO-expressed) (rMuMCP-3/CCL7) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Mouse MCP-3/CCL7 (CHO-expressed) (rMuMCP-3/CCL7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL7 is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses through binding to its receptors to mediate the recruitment of immune cells. Abnormal CCL7 expression is associated with certain immune diseases. CCL7 alsoplays a pivotal role in tumorigenesis[1]. |