Recombinant Mouse MCP-3/CCL7是趋化因子和引诱剂,用于各种白细胞,包括单核细胞和嗜中性粒细胞。 Synonyms rMuMCP-3/CCL7; C-C motif chemokine 7; MCP3; SCYA7 ; 重组小鼠MCP-3/CCL7 Species MouseSource E. coli Accession Q03366 Gene ID 20306 Molecular Weight Approximately 8.5 kDa AA Sequence QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP Biological Activity Full biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 100-300 ng/ml. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 2× PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Mouse MCP-3/CCL7 (rMuMCP-3/CCL7) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Mouse MCP-3/CCL7 (rMuMCP-3/CCL7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL7 is a chemotactic factor and attractant for various kinds of leukocytes, including monocytes and neutrophils. CCL7 is widely expressed in multiple cell types and can participate in anti-inflammatory responses through binding to its receptors to mediate the recruitment of immune cells. Abnormal CCL7 expression is associated with certain immune diseases. CCL7 alsoplays a pivotal role in tumorigenesis[1]. |