Recombinant Human MIG/CXCL9 是一种趋化因子,能够与 CXCR3 结合,与几种恶性肿瘤的肿瘤进展、免疫逃逸及血管生成有关。 Synonyms rHuMIG/CXCL9; C-X-C motif chemokine 9; SCYB9 ; 重组人 MIG/CXCL9 Species HumanSource E. coli Accession Q07325 Gene ID 4283 Molecular Weight Approximately 11.7 kDa AA Sequence TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLKNGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK VRKSQRSRQK KTT Biological Activity Full biological activity determined by a chemotaxis bioassay using human peripheral blood T-lymphocytes is in a concentration range of 10-100 ng/mL. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 50 mM NaCl. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human MIG/CXCL9 (rHuMIG/CXCL9) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability Lyophilized recombinant Human MIG/CXCL9 (rHuMIG/CXCL9) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Monokine induced by interferon-gamma (MIG/CXCL9) is a chemokine binding to CXCR3, associated with tumor progression, immune escape, and angiogenesis in several malignancies[1]. |