Recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 是一种 CC 趋化因子配体，受体为 CCR6。
Synonyms
rMuMIP-3α/CCL20; C-C motif chemokine 20; MIP3A; SCYA20 ; 重组小鼠巨噬细胞炎性蛋白-3 alpha/CCL20
Species
MouseSource
E. coli Accession
O89093 Gene ID
20297 Molecular Weight
Approximately 8.0 kDa AA Sequence
ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM Biological Activity
Full biological activity determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 (rMuMIP-3α/CCL20) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Mouse Macrophage Inflammatory Protein-3 alpha/CCL20 (rMuMIP-3α/CCL20) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CCL20 is a C-C motif chemokine ligand, which has C-C motif Chemokine Receptor 6 (CCR6) as its sole receptor and tissues producing CCL20 recruit CCR6 expressing immune cells[1]. The CCL20/CCR6 axis is also involved in various autoimmune diseases and in other cancers besides HCC[2]. |
