Recombinant Human MIP-5/CCL15 是一种趋化因子,对髓细胞如树突状细胞、单核细胞、中性粒细胞和一些 T 淋巴细胞具有很强的趋化性。 Synonyms rHuMIP-5/CCL15; C-C motif chemokine 15; HCC-2; SCYA15; NCC3 ; 重组人 MIP-5/CCL15 Species HumanSource E. coli Accession Q16663 Gene ID 6359 Molecular Weight Approximately 10.2 kDa AA Sequence QFINDAETEL MMSKLPLENP VVLNSFHFAA DCCTSYISQS IPCSLMKSYF ETSSECSKPG VIFLTKKGRQ VCAKPSGPGV QDCMKKLKPY SI Biological Activity The ED50 is <2 μg/mL as measured by CHO cells transfected with human CCR1, corresponding to a specific activity of >500 units/mg. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human MIP-5/CCL15 (rHuMIP-5/CCL15) to 100 µg/mL using ddH2O. Storage & Stability Lyophilized recombinant Human MIP-5/CCL15 (rHuMIP-5/CCL15) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background CCL15 is a chemokine with a strong chemotactic activity for myeloid cells such as dendritic cells, monocytes, neutrophils and some T-lymphocytes[1]. Recombinant Human CCL15 is the most abundant chemokine in follicular thyroid carcinoma (FTC) compared with follicular adenoma (FA)[2]. |