Recombinant Human TARC/CCL17 是一种新型可溶性的 T 细胞转移调节因子
Synonyms
rHuTARC/CCL17; C-C motif chemokine 17; SCYA17 ; 重组人源胸腺活化调节因子
Species
HumanSource
E. coli Accession
Q92583 Gene ID
6361 Molecular Weight
Approximately 8.1 kDa AA Sequence
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S Biological Activity
Full biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM PB, pH 7.4, 150 mM NaCl. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human TARC/CCL17 (rHuTARC/CCL17) to 0.1-1.0 mg/mL using sterile distilled water or aqueous buffer containing 0.1% BSA. Storage & Stability
Lyophilized recombinant Human TARC/CCL17 (rHuTARC/CCL17) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Recombinant Human TARC/CCL17 triggers secondary inflammatory events, aggravating asthma pathogenesis[1]. Treg migration toward epithelial cells is regulated by certain chemokines, including TARC/CCL17[2]. |
