Recombinant Rat ThymusChemokine 1/CXCL7 (CHO-expressed) 能够刺激细胞有丝分裂的发生、细胞外基质合成、糖代谢和纤溶酶原激活剂合成等多个过程。
Synonyms
rRtThymusChemokine-1/CXCL7; Ppbp; Rtck1 ; 重组大鼠CXC 趋化因子7 (CHO 细胞表达)
Species
RatSource
CHO Accession
Q99ME0 Gene ID
246358 Molecular Weight
Approximately 9.8 kDa AA Sequence
IELRCRCTNT LSGIPLNSIS RVNVFRPGAH CDNVEVIATL KNGKEVCLDP TAPMIKKIVK KI Biological Activity
The ED50 is <300 ng/mL as measured by CHO-K1/Gα15/rCXCR2 cells (human Gα15 and rat CXCR2 stably expressed in CHO-K1 cells). Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Rat ThymusChemokine-1/CXCL7 (CHO-expressed) (rRtThymusChemokine-1/CXCL7) to 100 μg/mL using ddH2O or PBS. Storage & Stability
Lyophilized recombinant Rat ThymusChemokine-1/CXCL7 (CHO-expressed) (rRtThymusChemokine-1/CXCL7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
CXCL7 stimulates various processes including mitogenesis, synthesis of extracellular matrix, glucose metabolism and synthesis of plasminogen activator[1]. CXCL7 has been shown to stimulate neutrophils for chemotaxis over an extremely wide range of stimulus concentrations, for the degranulation of lysosomal enzymes, and to up-regulate adhesion molecules on some cells[2]. |
