Recombinant Human VEGF-D (HEK293-expressed) 是一种促进血管再生和淋巴再生的调节因子。 Synonyms rHuVEGF-D; Vascular endothelial growth factor D; FIGF ; 重组人源血管内皮生长因子D (HEK293-expressed) Species HumanSource CHO Accession O43915 Gene ID 2277 Molecular Weight 18-19 kDa AA Sequence FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR Biological Activity The ED50 is <1 μg/mL as measured by HUVEC cells. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS. Endotoxin Level <0.2 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human VEGF-D (HEK293-expressed) (rHuVEGF-D) to 100 μg/mL using ddH2O or PBS. Storage & Stability Lyophilized recombinant Human VEGF-D (HEK293-expressed) (rHuVEGF-D) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background VEGF-D, a powerful lymphangiogenic and angiogenic growth factor, is also a major regulator of chylomicron metabolism in mice[1]. Vascular endothelial growth factor D (VEGF-D) has important functions in lymphangiogenesis and angiogenesis. High plasma levels of VEGF-D have been associated with incidence of heart failure. The association of VEGF-D with atrial fibrillation (AF) and stroke is unclear and we hypothesised that VEGF-D could also be associated with incidence of AF and ischaemic stroke[2]. |