Recombinant Human Fibroblast Growth Factor 8a 是 FGF-8 的亚型，FGF-8 是胚胎发育过程中的一个重要因子，参与前列腺癌的进展。
Synonyms
rHuFGF-8a; AIGF; HBGF-8 ; 重组人成纤维细胞生长因子 8a
Species
HumanSource
E. coli Accession
P55075 Gene ID
2253 Molecular Weight
Approximately 21.3 kDa AA Sequence
MQHVREQSLV TDQLSRRLIR TYQLYSRTSG KHVQVLANKR INAMAEDGDP FAKLIVETDT FGSRVRVRGA ETGLYICMNK KGKLIAKSNG KGKDCVFTEI VLENNYTALQ NAKYEGWYMA FTRKGRPRKG SKTRQHQREV HFMKRLPRGH HTTEQSLRFE FLNYPPFTRS LRGSQRTWAP EPR Biological Activity
The ED50 is <500 ng/mL as measured by 3T3 cells, corresponding to a specific activity of >2 × 103 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Fibroblast Growth Factor 8a (rHuFGF-8a) to 100 µg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human Fibroblast Growth Factor 8a (rHuFGF-8a) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Fibroblast Growth Factor 8 is an essential factor during embryonic development, overexpressed in several tumor types. Fibroblast Growth Factor 8 stimulates anti-apoptotic pathways and prevents tumor cell death[1]. |
