Recombinant Human gAcrp30/Adipolean 是脂联素的头状球部，调节脂肪酸和葡萄糖代谢。
Synonyms
rHugAcrp30/Adipolean; Adiponectin; ACRP30; APM-1; ADIPOQ; ACDC ; 重组人 gAcrp30/Adipolean
Species
HumanSource
E. coli Accession
Q15848 Gene ID
9370 Molecular Weight
Approximately 16.6 kDa AA Sequence
KGEPGEGAYV YRSAFSVGLE TYVTIPNMPI RFTKIFYNQQ NHYDGSTGKF HCNIPGLYYF AYHITVYMKD VKVSLFKKDK AMLFTYDQYQ ENNVDQASGS VLLHLEVGDQ VWLQVYGEGE RNGLYADNDN DSTFTGFLLY HDTN Biological Activity
The ED50 is <10 µg/mL as measured by M1 cells, corresponding to a specific activity of >100 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human gAcrp30/Adipolean (rHugAcrp30/Adipolean) to 100 µg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human gAcrp30/Adipolean (rHugAcrp30/Adipolean) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Adiponectin is a 30-kDa adipose-derived hormone that appears to play an important role in regulating energy homeostasis and insulin sensitivity. The globular head group of adiponectin (gAcrp30) reduces plasma glucose levels and ameliorates insulin resistance in mice[1]. |
