Recombinant Human HVEM, Fc Chimera (Sf9 insect cells-expressed) 是一种疱疹病毒的进入介质，介导多种野生型两种血清型 HSV 的进入。
Synonyms
rHuHVEM, Fc Chimera; TNFRSF14; TR2; CD270; HVEA ; 重组人 HVEM Fc 嵌合体 (Sf9 昆虫细胞表达)
Species
HumanSource
Sf9 insect cells Accession
Q92956 Gene ID
8764 Molecular Weight
Approximately 45 kDa AA Sequence
LPSCKEDEYP VGSECCPKCS PGYRVKEACG ELTGTVCEPC PPGTYIAHLN GLSKCLQCQM CDPAMGLRAS RNCSRTENAV CGCSPGHFCI VQDGDHCAAC RAYATSSPGQ RVQKGGTESQ DTLCQNCPPG TFSPNGTLEE CQHQTKRSCD KTHTCPPCPA PELLGGPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPAP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGK Biological Activity
The ED50 is <0.1 µg/mL as measured by 929 cells, corresponding to a specific activity of >1 × 104 units/mg. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS. Endotoxin Level
<0.2 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human HVEM, Fc Chimera (Sf9 insect cells-expressed) (rHuHVEM, Fc Chimera) to 100 µg/mL using ddH2O. Storage & Stability
Lyophilized recombinant Human HVEM, Fc Chimera (Sf9 insect cells-expressed) (rHuHVEM, Fc Chimera) is stored at -20°C. After reconstitution, it is stable at 4°C for 2 weeks or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
HVEM mediates the entry of several wild-type HSV strains of both serotypes. HVEM is active inmediating HSV-1 entry into human T lymphoblasts[1]. |
