Recombinant Human Thioredoxin/TXN 是一种控制细胞氧化还原平衡的硫醇氧化还原酶。
Synonyms
rHuThioredoxin/TXN, His; Trx; ADF; TRX1 ; 重组人硫氧还蛋白，His
Species
HumanSource
E. coli Accession
P10599 Gene ID
7295 Molecular Weight
Approximately 13.9 kDa AA Sequence
HHHHHHMVKQ IESKTAFQEA LDAAGDKLVV VDFSATWCGP CKMIKPFFHS LSEKYSNVIF LEVDVDDCQD VASECEVKCM PTFQFFKKGQ KVGEFSGANK EKLEATINEL V Biological Activity
Its ability to catalyze the reduction of insuline by precipitation reaction measured by absorbance at 650 nm. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM PB, 1 mM EDTA, 2 mM DTT, pH 7.2. Endotoxin Level
<1.0 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Thioredoxin/TXN, His (rHuThioredoxin/TXN, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Thioredoxin/TXN, His (rHuThioredoxin/TXN, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Thioredoxins are small thiol-oxidoreductase enzymes that control cellular redox homeostasis[1]. Human thioredoxin acts as a danger-associated molecular pattern (DAMP) on the immune system and is released upon stress from skin cells. Human thioredoxin leads to the release of IL-13 and IL-10 from human peripheral blood mononuclear cells[2]. |
