Synonyms rHuAcyl-coenzyme A thioesterase 13, His; ACOT-13; Acyl-coenzyme A thioesterase 13 ; 重组人酰基辅酶 A 硫酯酶 13,His (HEK293 细胞表达) Species HumanSource HEK 293 Accession Q9NPJ3 Gene ID 55856 Molecular Weight Approximately 15.9 kDa AA Sequence TSMTQSLREV IKAMTKARNF ERVLGKITLV SAAPGKVICE MKVEEEHTNA IGTLHGGLTA TLVDNISTMA LLCTERGAPG VSVDMNITYM SPAKLGEDIV ITAHVLKQGK TLAFTSVDLT NKATGKLIAQ GRHTKHLGNH HHHHH Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Acyl-coenzyme A thioesterase 13, His (HEK293-expressed) (rHuAcyl-coenzyme A thioesterase 13, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Acyl-coenzyme A thioesterase 13, His (HEK293-expressed) (rHuAcyl-coenzyme A thioesterase 13, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Acyl-coenzyme A thioesterase 13 (ACOT13), also known as thioesterase superfamily member 2 (Them2), belongs to the mammalian acyl-CoA thioesterase family. ACOT13 is a homotetrameric hotdog fold thioesterase, and is enriched in oxidative tissues, associated with mitochondria, and relatively specific for long chain fatty acyl-CoA substrates. ACOT13 plays a key role in hepatic lipid and glucose metabolism. ACOT13 is essential for the cell sustained proliferation and is co-localized with microtubules[1][2]. |