Recombinant Human Activin receptor type 2A, His (HEK293-expressed) 是一种在 HEK293 细胞中表达的人重组蛋白，由 ACVR2A 基因编码，具有 His 标签。Activin A receptor 是结合 Activin A。Activin A 可增加巨噬细胞中的炎性细胞因子[1]。
Synonyms
rHuActivin receptor type 2A, His; ACVR-2A; Activin receptor type 2A
Species
HumanSource
HEK 293 Accession
P27037 Gene ID
92 Molecular Weight
Approximately 32.0 kDa AA Sequence
AILGRSETQE CLFFNANWEK DRTNQTGVEP CYGDKDKRRH CFATWKNISG SIEIVKQGCW LDDINCYDRT DCVEKKDSPE VYFCCCEGNM CNEKFSYFPE MEVTQPTSNP VTPKPHHHHH H Biological Activity
Data is not available. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM PB, 150 mM NaCl, 1 mM DTT, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Activin receptor type 2A, His (HEK293-expressed) (rHuActivin receptor type 2A, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Activin receptor type 2A, His (HEK293-expressed) (rHuActivin receptor type 2A, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Activin A is a member of the transforming growth factor-β superfamily and regulates a wide variety of cellular events, including regulation of growth and metastasis of cancer cells, apoptosis, proliferation, and differentiation of human embryonic stem cells. Activin A is also a critical mediator of inflammation[1]. |
