Recombinant Human ADP-ribosylarginine hydrolase, His 是带有 N 末端 His 标签的人重组 ADP-核糖基精氨酸水解酶 (ADPRH)，在大肠杆菌中表达。
Synonyms
rHuADP-ribosylarginine hydrolase, His; ADPRH; ARH-1; ADP-ribosylarginine hydrolase ; 重组人 ADP-核糖基精氨酸水解酶，His
Species
HumanSource
E. coli Accession
P54922 Gene ID
141 Molecular Weight
Approximately 39.0 kDa AA Sequence
HHHHHHMEKY VAAMVLSAAG DALGYYNGKW EFLQDGEKIH RQLAQLGGLD ALDVGRWRVS DDTVMHLATA EALVEAGKAP KLTQLYYLLA KHYQDCMEDM DGRAPGGASV HNAMQLKPGK PNGWRIPFNS HEGGCGAAMR AMCIGLRFPH HSQLDTLIQV SIESGRMTHH HPTGYLGALA SALFTAYAVN SRPPLQWGKG LMELLPEAKK YIVQSGYFVE ENLQHWSYFQ TKWENYLKLR GILDGESAPT FPESFGVKER DQFYTSLSYS GWGGSSGHDA PMIAYDAVLA AGDSWKELAH RAFFHGGDSD STAAIAGCWW GVMYGFKGVS PSNYEKLEYR NRLEETARAL YSLGSKEDTV ISL Biological Activity
Data is not available. Appearance
Solution Formulation
Supplied as a 0.2 μm filter solution of 20 mM PB, 150 mM NaCl, 50% Glycerol, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
N/A Storage & Stability
Recombinant Human ADP-ribosylarginine hydrolase, His (rHuADP-ribosylarginine hydrolase, His) is stored at -20°C. It is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Shipping with dry ice. Background
ADP-ribosylarginine hydrolase (ADPRH; ARH-1) belongs to the ADP-ribosylglycohydrolase family. ADPRH cleaves α-ADP-ribose-arginine (protein), produced in the transferase-catalyzed reaction, to regenerate the arginine-guanidino group. ADPRH catalyzes removal of mono-ADP-ribose from arginine residues of proteins in the ADP-ribosylation cycle. The dysregulation of mono-ADP ribosylation of arginines in proteins by ADPRH can affect cell proliferation and tumorigenesis. ADPRH cDNAs from human, rat, and mouse tissues share 82% similarity of deduced amino acid sequences[1][2]. |
