Recombinant Human Aldehyde dehydrogenase family 3 member A1, His (HEK293-expressed) 是在 N 端带有 His 标签的人重组 ALDH3A1,在 HEK293 细胞中表达。 Synonyms rHuAldehyde dehydrogenase family 3 member A1, His; ALDH-3A1; Aldehyde Dehydrogenase 3 member A1 ; 重组人类醛脱氢酶家族 3 成员 A1,His (HEK293 细胞表达) Species HumanSource HEK 293 Accession P30838 Gene ID 218 Molecular Weight Approximately 58.0 kDa AA Sequence MSKISEAVKR ARAAFSSGRT RPLQFRIQQL EALQRLIQEQ EQELVGALAA DLHKNEWNAY YEEVVYVLEE IEYMIQKLPE WAADEPVEKT PQTQQDELYI HSEPLGVVLV IGTWNYPFNL TIQPMVGAIA AGNSVVLKPS ELSENMASLL ATIIPQYLDK DLYPVINGGV PETTELLKER FDHILYTGST GVGKIIMTAA AKHLTPVTLE LGGKSPCYVD KNCDLDVACR RIAWGKFMNS GQTCVAPDYI LCDPSIQNQI VEKLKKSLKE FYGEDAKKSR DYGRIISARH FQRVMGLIEG QKVAYGGTGD AATRYIAPTI LTDVDPQSPV MQEEIFGPVL PIVCVRSLEE AIQFINQREK PLALYMFSSN DKVIKKMIAE TSSGGVAAND VIVHITLHSL PFGGVGNSGM GSYHGKKSFE TFSHRRSCLV RPLMNDEGLK VRYPPSPAKM TQHHHHHHH Biological Activity Data is not available. Appearance Lyophilized powder. Formulation Lyophilized after extensive dialysis against PBS, pH 7.4. Endotoxin Level <1 EU/μg, determined by LAL method. Reconstitution Reconstitute the lyophilized recombinant Human Aldehyde dehydrogenase family 3 member A1, His (HEK293-expressed) (rHuAldehyde dehydrogenase family 3 member A1, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability Lyophilized recombinant Human Aldehyde dehydrogenase family 3 member A1, His (HEK293-expressed) (rHuAldehyde dehydrogenase family 3 member A1, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping Room temperature in continental US; may vary elsewhere. Background Aldehyde dehydrogenase 3A1 (ALDH3A1) is an important member of the ALDH superfamily, which consists of NAD(P)+- dependent enzymes that oxidize a wide variety of endogenously produced and exogenously derived aldehydes to their corresponding carboxylic acids. ALDH3A1 is often overexpressed in esophagus-mucosa, minor salivary gland, nasal epithelium, tonsil and oral epithelium. ALDH3A1 has been shown to be upregulated in several cancer types, such as stomach cancer, lung cancer or oral squamous cell carcinoma (OSCC)[1]. |