Recombinant Human Amyloid-like Protein 1, His (HEK293-expressed) 也称作APLP1，在暴露于Mn 的模型中，其在额叶皮质的神经元中含量明显上升。
Synonyms
rHuAmyloid-like Protein 1, His; APLP-1; Amyloid-like Protein 1 ; 重组人淀粉样蛋白 1,His (HEK 293表达)
Species
HumanSource
HEK 293 Accession
P51693 Gene ID
333 Molecular Weight
18-20 kDa AA Sequence
GGSPGAAEAP GSAQVAGLCG RLTLHRDLRT GRWEPDPQRS RRCLRDPQRV LEYCRQMYPE LQIARVEQAT QAIPMERWCG GSRSGSCAHP HHQVVPFRCL PGEFVSEALL VPEGCRFLHQ ERMDQCESST RRHQEAQEAC SSQGLILHGS GMLLPCGSDR FRGVEYVCCP PHHHHHH Biological Activity
Data is not available. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PBS, 1 mM EDTA, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Amyloid-like Protein 1, His (HEK293-expressed) (rHuAmyloid-like Protein 1, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Amyloid-like Protein 1, His (HEK293-expressed) (rHuAmyloid-like Protein 1, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Human APLP1 gene has been mapped to the long arm of chromosome 19 in the same region containing a late-onset familial AD locus. APLP1 is a member of the amyloid precursor family. Increased APLP1 expression and revealed the presence of amyloid-β diffuse plaques. |
