Recombinant Human Angiopoietin-2, His (HEK293-expressed) 是内皮特异性Tie2受体的循环拮抗配体，被认为是内皮细胞活化的重要看门人。
Synonyms
rHuAngiopoietin-2, His; ANGPT2; ANG2; Angiopoietin-2 ; 重组人血管生成素 2
Species
HumanSource
HEK 293 Accession
O15123 Gene ID
285 Molecular Weight
30-35 kDa AA Sequence
KEEQISFRDC AEVFKSGHTT NGIYTLTFPN STEEIKAYCD MEAGGGGWTI IQRREDGSVD FQRTWKEYKV GFGNPSGEYW LGNEFVSQLT NQQRYVLKIH LKDWEGNEAY SLYEHFYLSS EELNYRIHLK GLTGTAGKIS SISQPGNDFS TKDGDNDKCI CKCSQMLTGG WWFDACGPSN LNGMYYPQRQ NTNKFNGIKW YYWKGSGYSL KATTMMIRPA DFHHHHHH Biological Activity
Data is not available. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against 20 mM MOPS, 150 mM NaCl, 10% CHAPS, pH 7.5. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Angiopoietin-2, His (HEK293-expressed) (rHuAngiopoietin-2, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Angiopoietin-2, His (HEK293-expressed) (rHuAngiopoietin-2, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Angiopoietins are peptides involved in embryonic vascular development. Of the four angiopoietins that have been identified, angiopoietin 1 and angiopoietin 2 (ANGPT1 and ANGPT2, respectively) are the best described. Angiopoietin 2, produced by endothelial cells, also binds to the Tie2 receptor and acts as an antagonistic factor without activating the receptor. |
