Recombinant Human Apolipoprotein A-I, His (HEK293-expressed) 在 HEK293 细胞中表达，N 端带有一个 His 标签。apolipoprotein A-I (ApoA-I) 是高密度脂蛋白 (HDL) 中的主要蛋白成分，与登革热病毒 (DV) 颗粒相关，并通过 SR-BI 增强病毒感染。
Synonyms
rHuApolipoprotein A-I, His; ApoA1; Apolipoprotein A-I
Species
HumanSource
HEK 293 Accession
P02647 Gene ID
335 Molecular Weight
Approximately 30.0 kDa AA Sequence
RHFWQQDEPP QSPWDRVKDL ATVYVDVLKD SGRDYVSQFE GSALGKQLNL KLLDNWDSVT STFSKLREQL GPVTQEFWDN LEKETEGLRQ EMSKDLEEVK AKVQPYLDDF QKKWQEEMEL YRQKVEPLRA ELQEGARQKL HELQEKLSPL GEEMRDRARA HVDALRTHLA PYSDELRQRL AARLEALKEN GGARLAEYHA KATEHLSTLS EKAKPALEDL RQGLLPVLES FKVSFLSALE EYTKKLNTQH HHHHH Biological Activity
Data is not available. Appearance
Lyophilized powder. Formulation
Lyophilized after extensive dialysis against PB, pH 7.4. Endotoxin Level
<1 EU/μg, determined by LAL method. Reconstitution
Reconstitute the lyophilized recombinant Human Apolipoprotein A-I, His (HEK293-expressed) (rHuApolipoprotein A-I, His) to 100 µg/mL using ddH2O or diluted with PBS. Storage & Stability
Lyophilized recombinant Human Apolipoprotein A-I, His (HEK293-expressed) (rHuApolipoprotein A-I, His) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage. Shipping
Room temperature in continental US; may vary elsewhere. Background
Apolipoprotein A1 (ApoA1) is a 28 kDa glycoprotein that is the major protein component of high density lipoprotein (HDL) particles. HDL particles play a central role in the reverse transport of cholesterol from peripheral tissues to the liver. In the past decade, reconstituted HDL (rHDL) has been employed as a therapeutic agent for treatment of atherosclerosis. The ability of rHDL to promote cholesterol efflux from peripheral cells has been documented to reduce the size of atherosclerotic plaque lesions[2]. |
